Patent — available for licensing
Electrochemical Sensors Based on Enzyme-Linked Immunosorbent Assay
A NASA invention available to explore as a licensing opportunity.
About this technology
Overview
Biological assays are ever evolving to move towards lower limits of detection and improved sensitivity. Improvements in trace biological molecule detection can have significant impact in healthcare, food safety and environmental safety industries. Detection of trace biological molecules can be critical to the diagnosis of early onset of diseases or infections. Researchers at NASA Ames Research Center developed an electrochemical, bead-based biological sensor based on Enzyme-Linked Immunosorbent Assay (ELISA) combining a magnetic concentration of signaling molecules and electrochemical amplification using wafer-scale fabrication of microelectrode arrays. Originally developed for the detection of the SARS-CoV-2 nucleoprotein, this invention can be easily modified to detect other environmental or human health biomarkers.